Assessment of respiratory muscles power and lung function tests in asthmatics, police women trainees and healthy obese adults in Khartoum state (2010-2013)
Asthma is one of the main respiratory health problems worldwide. Asthma diagnosis when moderate or severe is easy depending on wheezing & other symptoms, but mild and intermittent asthma could be a clinical challenge. Respiratory muscles power is indirectly measured through mouth pressures (maximal inspiratory pressure [MIP] and maximal expiratory pressure [MEP] ).Lung function and respiratory muscles power were measured in: 35 asthmatics before and after bronchodilators and 20 non asthmatic controls; 30 normal subjects and 15 asthmatics at 6:00 a.m and 6:00 p.m; 28 trained policewomen athletes and 31 matched untrained controls; 52 healthy obese subjects with body mass index (BMI) ≥ 30kg/m2 and 43 matched non obese subjects (BMI < 25kg/ m2). Significant increase in FVC, FEV1, PEFR, MEP and MIP were observed after bronchodilator test in asthmatics, at 6:00 p.m, in trained subjects compared to that obtained before bronchodilator test, at 6:00 a.m, in untrained subjects respectively. MEP and MIP significantly increased in obese compared to non-obese subjects with MEP is positively correlated with weight and % fat is negatively correlated to FVC and FEV1.Insignificant difference was detected in lung function between obese and non-obese subjects. The study concluded that respiratory muscles power (MEP and MIP) reversibility and variability testing could be potential sensitive tests in diagnosis of asthma and respiratory muscles power could be also a sensitive tool for assessment of athletes, performance. The normal lung function in obese subjects could be due to improved respiratory muscle power in them.
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